Etravirine - Bio-X ™

CAS: 269055-15-4

Ref. 3D-BA164437

Informação sobre produto

• Nome: Etravirine - Bio-X ™
• Sinónimos: Intelence4-[[6-Amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrileR 165335TMC 125
• Marca: Biosynth

Descrição

Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) medication used in the treatment of human immunodeficiency virus (HIV) infections. It works by blocking reverse transcriptase, an enzyme essential for replication of the virus, thereby preventing the virus from multiplying and spreading. Etravirine is often used in combination with other antiretroviral drugs to effectively treat HIV/AIDS. It is commonly prescribed for patients with virus strains that are resistant to other NNRTI medications due to mutations that confer resistance- mutations K103N and Y181C. Etravirine is a diarylpyrimidine (DAPY) and has conformational isomerism meaning that it binds reverse transcriptase in an fleible manner, under multiple conformations. The impact of specific point mutations in the virus is therefore lessened.

Propriedades químicas

• Peso molecular: 435.28 g/mol
• Fórmula: C₂₀H₁₅BrN₆O
• Pureza: Min. 95%
• Cor/forma: Powder