Calpain inhibitor XII

CAS: 181769-57-3

Ref. 3D-BC177426

Informação sobre produto

• Nome: Calpain inhibitor XII
• Sinónimos: [3-Methyl-1-[[[1-[oxo[(2-pyridinylmethyl)amino]acetyl]butyl]amino]carbonyl]butyl]-carbamic acid, phenylmethyl ester
• CAS: 181769-57-3

Descrição

Inhibitor of calpain, a calcium-dependent cysteine protease which is implicated in the calcium-mediated processes such as apoptosis and neuronal membrane excitability. Calpain inhibitor XII has antiviral properties as it can inhibit the main protease Mpro (3CLpro) from SARS-CoV-2 with IC50 of 0.45 μM.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 482.57 g/mol
• Fórmula: C₂₆H₃₄N₄O₅
• Pureza: Min. 95%
• Cor/forma: Powder
• InChI: InChI=1S/C26H34N4O5/c1-4-10-21(23(31)25(33)28-16-20-13-8-9-14-27-20)29-24(32)22(15-18(2)3)30-26(34)35-17-19-11-6-5-7-12-19/h5-9,11-14,18,21-22H,4,10,15-17H2,1-3H3,(H,28,33)(H,29,32)(H,30,34)
• Chave InChI: InChIKey=PLVWMBFPIAQRHK-UHFFFAOYSA-N
• SMILES: CCCC(NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1)C(=O)C(=O)NCc1ccccn1