2-Chloro-N-(5-methoxymethyl-[1,3,4]thiadiazol-2-yl)-acetamide

CAS: 876710-55-3

Ref. 3D-BKB71055

Informação sobre produto

• Nome: 2-Chloro-N-(5-methoxymethyl-[1,3,4]thiadiazol-2-yl)-acetamide
• Sinónimos: acetamide, 2-chloro-N-[5-(methoxymethyl)-1,3,4-thiadiazol-2-yl]-

Descrição

2-Chloro-N-(5-methoxymethyl-[1,3,4]thiadiazol-2-yl)-acetamide is an analog of the natural product 5-methoxy-[1,3,4]thiadiazole acetate. It has been found to be a potent inhibitor of sulfamoyl chloride hydrolase (EC 3.5.1.8) and carbonic anhydrase (EC 4.2.1.1). The inhibition constants for these enzymes were determined to be 2 x 10 M and 1 x 10 M respectively in vitro using purified enzymes and are both in the micromolar range in vivo following administration of the drug to mice bearing hypoxic tumors.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 221.66 g/mol
• Fórmula: C₆H₈ClN₃O₂S
• Pureza: Min. 95%