Rituximab - 10mg/ml solution

CAS: 174722-31-7

Ref. 3D-BR167936

Informação sobre produto

• Nome: Rituximab - 10mg/ml solution

Descrição

Rituximab is a glycosylated monoclonal antibody that binds to the CD20 cell surface protein which is widely expressed on B-cells. Through the binding of rituximab’s Fc portion, the antibody-dependent cellular cytotoxicity pathway (ADCC) and the complement-dependent cytotoxicity (CDC) pathway are initiated, both leading to B-cell lysis (Chisari, 2021). In addition, direct apoptosis can be the result of the inhibition of various B-cell signalling pathways. Rituximab is used in targeted therapy for chronic lymphocytic leukaemia (CLL), non-Hodgkin lymphoma (NHL) and some non-cancer pathologies, such as, multiple sclerosis (Johnson, 2001).

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 143.86 kg/mol
• Fórmula: C₆₄₁₆H₉₈₇₄N₁₆₈₈O₁₉₈₇S₄₄
• Pureza: Min. 95 Area-%
• Cor/forma: Colorless Clear Liquid