S 63845

CAS: 1799633-27-4

Ref. 3D-BS166833

Informação sobre produto

• Nome: S 63845
• Sinónimos: (?R)-?-[[(5S)-5-[3-Chloro-2-methyl-4-[2-(4-methyl-1-piperazinyl)ethoxy]phenyl]-6-(5-fluoro-2-furanyl)thieno[2,3-d]pyrimidin-4-yl]oxy ]-2-[[1-(2,2,2-trifluoroethyl)-1H-pyrazol-5-yl]methoxy]benzenepropanoic acid, Benzenepropanoic acid, α-[[(5S)-5-[3-chloro-2-methyl-4-[2-(4-methyl-1-piperazinyl)ethoxy]phenyl]-6-(5-fluoro-2-furanyl)thieno[2,3-d]pyrimidin-4-yl]oxy]-2-[[1-(2,2,2-trifluoroethyl)-1H-pyrazol-5-yl]methoxy]-, (αR)-, (αR)-α-[[(5S)-5-[3-Chloro-2-methyl-4-[2-(4-methyl-1-piperazinyl)ethoxy]phenyl]-6-(5-fluoro-2-furanyl)thieno[2,3-d]pyrimidin-4-yl]oxy]-2-[[1-(2,2,2-trifluoroethyl)-1H-pyrazol-5-yl]methoxy]benzenepropanoic acid, S-63845

Descrição

S 63845 is a novel anti-cancer drug that belongs to the class of ubiquitin ligases. It has been shown to induce apoptosis in cancer cells and inhibit tumor growth in vivo. S 63845 also inhibits the phosphorylation of cyclin D2, which may be a potential biomarker for sclerosing cholangitis (SCC). This compound is highly cytotoxic and has been found to be effective against subcutaneous tumors in mice. S 63845 also inhibits the proliferation of primary cells and has been shown to significantly reduce hepatic steatosis, as well as inhibiting inflammation caused by toll-like receptor 4 activation.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 829.26 g/mol
• Fórmula: C₃₉H₃₇ClF₄N₆O₆S
• Pureza: Min. 95%
• Cor/forma: Solid