Informação sobre produto
- Emavusertib
- 4-Oxazolecarboxamide, N-[5-[(3R)-3-hydroxy-1-pyrrolidinyl]-2-(4-morpholinyl)oxazolo[4,5-b]pyridin-6-yl]-2-(2-methyl-4-pyridinyl)-
- (R)-N-{5-(3-Hydroxypyrrolidin-1-yl)-2-morpholinooxazolo[4,5-b]pyridin-6-yl}-2-(2-methylpyridin-4-yl)oxazole-4-carboxamide
- CA 4948
- N-[5-[(3R)-3-Hydroxy-1-pyrrolidinyl]-2-(4-morpholinyl)oxazolo[4,5-b]pyridin-6-yl]-2-(2-methyl-4-pyridinyl)-4-oxazolecarboxamide
Ca-4948 is a molecule that has been shown to have anticancer activity in vivo. It activates toll-like receptor 4 (TLR4) and induces tumor necrosis factor (TNF) production. Ca-4948 is well tolerated with low toxicity, and has pharmacokinetic properties that are suitable for oral administration. In the submandibular gland of mice, Ca-4948 had antitumor response. This drug was also effective at suppressing subcutaneous tumors in a murine xenograft model, but did not show clinical response in clinical studies with patients with cancer.
Propriedades químicas
Consulta técnica sobre: 3D-BXC34414 Ca-4948
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