Angiotensin (Human, 1-7)

CAS: 51833-78-4

Ref. 3D-CRB1000803

Informação sobre produto

• Nome: Angiotensin (Human, 1-7)
• Sinónimos: H-DRVYIHP-OH, Angiotensin I/II (1-7), H-Asp-Arg-Val-Tyr-Ile-His-Pro-OH, L-alpha-aspartyl-N~5~-(diaminomethylidene)-L-ornithyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-proline

Descrição

Angiotensin 1-7 (Ang-(1-7)) is a component of the renin angiotensin system RAS. Ang-(1-7) is produced by angiotensin-converting enzyme 2 (ACE2), from the angiotensin II (Ang-II) peptide, as well as by prolylendopeptidase (PEP) and neutral endopeptidase (NEP) which produce Ang-(1-7) directly from angiotensin I (Ang-I).Ang-(1-7) broadly opposes Ang-II actions. Ang-(1-7) has vasodilatory and anti-oxidative effects, and exerts protective actions in hypertension, diabetes, and other cardiovascular disorders, Ang-(1-7) therefore represents a promising therapeutic target for cardiovascular and metabolic diseases. Ang-(1-7) exerts its actions via its G-protein-coupled receptor, Mas. This novel arm of the RAS has effects that counterbalance those mediated by the classical ACE/Ang-II pathway.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 899.01 g/mol
• Fórmula: C₄₁H₆₂N₁₂O₁₁
• Pureza: Min. 95%
• Cor/forma: Powder