Informação sobre produto
Nome:Biotin-DAG Peptide
Sinónimos:
- [Cyc(1,9)]Biot-CDAGRKQKC-OHBiotin-CDAGRKQKC-acid
- (Disulfide bridge: Cys1 - Cys9)Biotin-Cys-Asp-Ala-Gly-Arg-Lys-Gln-Lys-Cys-OH
- (D isulfide bridge: Cys1 - Cys9 )a-Calcitonin gene-related peptide (mous
Marca:Biosynth
Descrição:Cyclic DAG peptide targets connective tissue growth factor (CTGF/CCN2), present in the extracellular matrix, endothelial cells and overexpressed in several brain diseases. CTGF is a matricellular protein that acts as a regulator of several cellular functions, including cell adhesion, migration, mitogenesis, differentiation, and survival. CTGF is up regulated in Alzheimer's disease, Parkinson's disease, brain injury, glioblastoma, and cerebral infarction.DAG peptide has been shown to home to the brain in mouse models of glioblastoma, traumatic brain injury, and Parkinson's disease when exogenously delivered, making it an attractive target for the treatment of glioblastoma. DAG may be of use as a tool to enhance delivery of therapeutics and imaging agents to sites of brain diseases.
Aviso:Os nossos productos estão destinados exclusivamente para uso em laboratório. Para qualquer outra aplicação, por favor entre em contacto.
Propriedades químicas
Peso molecular:1,231.5 g/mol