Cyclo(RGDfK)

Ref. 3D-CRB1001046

Informação sobre produto

• Nome: Cyclo(RGDfK)
• Sinónimos: [LacN(0,5)]RGD(dF)KCyclo(RGDfK) where f is D-PhenylalanineCyclo(Arg-Gly-Asp-[D-Phe]-Lys)where D-Phe is D-Phenylalaninec(RGDfK)c( -RGDfK)

Descrição

The cyclic pentapeptide cyclo(Arg-Gly-Asp-[D-Phe]-Lys) is a highly potent and selective inhibitor for the alphavβ3 integrin receptor. A related compound, cyclo(Arg-Gly-Asp-[D-Phe]-Val), is a promising anticancer drug candidate- it inhibits angiogenesis and induces apoptosis in vascular cells.Cyclic RGD-containing peptides are selective antagonists of integrins, proteins that play important roles in cell-cell and cell-matrix interactions. In a suitably labelled form, these peptides may serve as useful tools for diagnostic imaging and peptide targeted therapy of some types of cancer.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 603.3 g/mol
• Cor/forma: Powder