AYPGFK Protease-Activated Receptor-4 (PAR-4)

Ref. 3D-CRB1001374

Informação sobre produto

• Nome: AYPGFK Protease-Activated Receptor-4 (PAR-4)
• Sinónimos: H-AYPGKF-NH2

Descrição

Protease activated receptors (PARs) are a distinctive four-member family of seven transmembrane G protein-coupled receptors (GPCRs) widely expressed in inflammatory cells. PARs are cleaved by certain serine proteases to expose a tethered ligand domain, this ligand domain then binds to and activates the receptors to initiate multiple signalling cascades. These PAR-activating proteases therefore represent PAR agonists. This PAR-4 agonist peptide represents the N-terminal sequence of the 'tethered ligand' and is therefore capable of activating the receptor independently of N-terminal proteolysis.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 680.4 g/mol