Informação sobre produto
- 1-Methyl-2-phenyl indole
- 1-methyl-2-phenyl-1H-indole
- 1H-Indole, 1-methyl-2-phenyl-
- 2-Phenyl-1-methylindole
- 2-Phenyl-N-methylindole
- Indole, 1-methyl-2-phenyl-
- N-Methyl-2-phenylindole
- NSC 63793
1-Methyl-2-phenylindole (1MPI) is an adenine nucleotide analog, which has been shown to cause oxidative injury in the cervical cancer cells. The hydrochloric acid present in 1MPI reacts with the hydroxyl group on the indole ring to form a reactive species that can damage cellular macromolecules and DNA. 1MPI also causes mitochondrial dysfunction and reduced ATP levels, leading to cell death. It has been shown to be effective against diabetic neuropathy and reduce the production of malondialdehyde in tissue culture experiments. This drug is also capable of inducing apoptosis by releasing nitrous oxide and activating caspases.
Propriedades químicas
Consulta técnica sobre: 3D-DAA55824 1-Methyl-2-phenylindole
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