Informação sobre produto
2,6-Diamino-4-hydroxyquinazoline (DAHQ) is a configurable molecule that has shown cytotoxic effects on cancer cells. It also inhibits the efflux pump activity of bacteria, which is essential for bacterial survival in an acidic environment. DAHQ has been shown to be effective against Gram-positive and Gram-negative bacteria. The pharmacophore of DAHQ consists of a hydroxyl group and an acid complex that are connected by a hydrogen bond. This configuration was obtained through sequence data and computational analysis, and it is thought to inhibit the protonation of the amino group in histidine residues found in the bacterial protein pump.
Propriedades químicas
Consulta técnica sobre: 3D-DCA74523 2,6-Diamino-4-hydroxyquinazoline
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