Informação sobre produto
- α-Maleimidopropionyl-ω-succinimidyl-2(ethylene glycol)
- Mal-PEG2-NHS
- alpha-MaleiMidopropionyl-oMega-succiniMidyl-2(ethylene glycol)
- 3-[2-[2-[[3-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]propanoic acid 2,5-dioxo-1-pyrrolidinyl ester
- MaleiMide-PEG2-succiniMidyl ester
MAL-dPEG2-NHS ester is a molecule that belongs to the class of peptide conjugates. It has been designed for use in pancreatic cancer imaging. MAL-dPEG2-NHS ester is composed of a mitochondria targeting sequence and an NHS ester at its C-terminus. The conjugate was synthesized by reacting the amine group of the NHS ester with the free carboxyl group of MAL, forming an amide bond. This reaction can be performed under mild conditions, which minimizes side reactions and reduces the need for purification steps.
The conjugate was shown to have high molecular weight (approximately 10 kDa), enabling it to be detected by electron microscopy and fluorescence microscopy techniques, such as localization microscopy or supercritical fluid microscopy. The conjugate also exhibits strong mitochondrial protein binding properties, which may help improve vaccine development strategies against cancer cells that are
Propriedades químicas
Consulta técnica sobre: 3D-DPG-5765 MAL-dPEG®2-NHS Ester
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