Naphthol AS-BI N-acetyl-b-D-glucosaminide

CAS: 3395-37-7

Ref. 3D-EN06141

Informação sobre produto

• Nome: Naphthol AS-BI N-acetyl-b-D-glucosaminide
• Sinónimos: 2-Naphth-o-anisidide, 3-[(2-acetamido-2-deoxy-β-<span class="text-smallcaps">D</span>-glucopyranosyl)oxy]-7-bromo-, 2-Naphthalenecarboxamide, 3-[[2-(acetylamino)-2-deoxy-β-<span class="text-smallcaps">D</span>-glucopyranosyl]oxy]-7-bromo-N-(2-methoxyphenyl)-, 3-[(2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-7-bromo-N-(2-methoxyphenyl)naphthalene-2-carboxamide, 3-[[2-(Acetylamino)-2-deoxy-β-<span class="text-smallcaps">D</span>-glucopyranosyl]oxy]-7-bromo-N-(2-methoxyphenyl)-2-naphthalenecarboxamide, Glucopyranoside, 6-bromo-3-[(o-methoxyphenyl)carbamoyl]-2-naphthyl 2-acetamido-2-deoxy-+, β-<span class="text-smallcaps">D</span>-
• CAS: 3395-37-7

Descrição

Naphthol AS-BI N-acetyl-b-D-glucosaminide is an enzyme inhibitor that is used in the treatment of Gaucher's disease. The enzyme it inhibits is β-glucosidase, which breaks down glucocerebrosides in the lysosomes of cells. This drug prevents the breakdown of glucocerebrosides and increases their concentration in cells, which reduces the symptoms of Gaucher's disease. Naphthol AS-BI N-acetyl-b-D-glucosaminide has been shown to be effective against wild type and mutant forms of the enzyme. However, it does not work against patients who are homozygous for a mutation in exon 1 of the βglu gene that codes for βglu protein.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 575.41 g/mol
• Fórmula: C₂₆H₂₇BrN₂O₈
• Pureza: Min. 97 Area-%
• Cor/forma: White Powder