3-Aminobenzeneboronic acid
CAS: 30418-59-8
Ref. 3D-FA03380
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Informação sobre produto
- 3-Aminobenzeneboronicacid
- 3-Aminophenyl(dihydroxy)borane
- B-(3-Aminophenyl)boronic acid
- Benzeneboronic acid, m-amino-
- Boronic acid, (3-aminophenyl)-
- Boronic acid, B-(3-aminophenyl)-
- m-Aminobenzeneboronic acid
- m-Aminophenylboronic acid
3-Aminobenzeneboronic acid (3AB) is a colorless solid that is soluble in water and alcohol. It has a phase transition temperature of 170°C, a molar mass of 114.1 g/mol, and has two enantiomers. 3AB is a potent inhibitor of human basic fibroblast growth factor receptor 2 (HER2), which is a protein present on the cell surface that promotes tumor cell growth and survival in certain cancers, such as breast cancer. 3AB also inhibits prostate cancer cells by preventing sodium citrate from binding to the HER2 receptor. 3AB binds to human immunoglobulin G (IgG) with an affinity constant of 1 × 10 M and fluoresces under UV light at 355 nm. Kinetic data for the enzyme substrate dopamine shows that 3AB's inhibition can be attributed to competitive inhibition, where the enzyme competes with dopamine for access to its substrate. This compound has been shown to be useful in
Propriedades químicas
Consulta técnica sobre: 3D-FA03380 3-Aminobenzeneboronic acid
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