Ac-Asp-Glu-Val-Asp-AMC ammonium salt

CAS: 169332-61-0

Ref. 3D-FA110568

Informação sobre produto

• Nome: Ac-Asp-Glu-Val-Asp-AMC ammonium salt
• Sinónimos: Ac-DEVD-AMC ammonium salt, Ac-Asp-Glu-Val-Asp-AMC, Ac-Devd-Amc

Descrição

Ac-Asp-Glu-Val-Asp-AMC ammonium salt is a small molecule that is used as a tool to study apoptosis in vitro. Ac-Asp-Glu-Val-Asp-AMC ammonium salt induces apoptosis by blocking the mitochondrial membrane potential and inducing the release of cytochrome c from mitochondria into the cytoplasm. This drug also induces activation of caspase 3, which initiates the cascade of events leading to cell death. Ac-Asp-Glu-Val-Asp-AMC ammonium salt has been shown to have an antiangiogenic effect on hl60 cells. This effect may be due to its ability to inhibit expression of survivin, a protein that protects cells from apoptosis. The efficacy of this drug in an experimental model has been shown to be dependent on toll like receptor (TLR) signaling pathways and mitochondrial function.br>

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 692.67 g/mol
• Fórmula: C₃₀H₃₇N₅O₁₃•NH₃
• Pureza: Min. 97 Area-%
• Cor/forma: Powder