Ac-Ile-Glu-Thr-Asp-AMC

CAS: 348079-17-4

Ref. 3D-FA110583

Informação sobre produto

• Nome: Ac-Ile-Glu-Thr-Asp-AMC
• Sinónimos: Ac-IETD-AMC, Caspase-3 Precursor Protease Substrates

Descrição

Ac-Ile-Glu-Thr-Asp-AMC is a reactive, nonsteroidal anti-inflammatory drug that inhibits the activity of survivin, which is an important protein for the survival of prostate cancer cells. Ac-Ile-Glu-Thr-Asp-AMC also inhibits mitochondrial membrane potential in prostate cancer cells and normal peripheral blood mononuclear cells, leading to apoptosis. The biochemical properties of Ac-Ile-Glu-Thr-Asp-AMC are similar to those of other NSAIDs. This drug has been shown to inhibit protein synthesis in experimental models and hydrochloric acid causes mitochondrial membrane depolarization, which triggers apoptosis.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 675.68 g/mol
• Fórmula: C₃₁H₄₁N₅O₁₂
• Pureza: Min. 95 Area-%
• Cor/forma: Powder