N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine

CAS: 152460-10-1

Ref. 3D-FA15934

Informação sobre produto

• Nome: N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
• Sinónimos: 4-Methyl-3-[4-(3-pyridyl)pyrimidin-2-ylamino]aniline4-Methyl-N'-[4-(pyridin-3-yl)pyrimidin-2-yl]benzene-1,3-diamineN-(5-Amino-o-to lyl)-4-(3-pyridyl)-2-pyrimidinamine
• Marca: Biosynth
• Descrição: Imatinib is an anticancer drug that belongs to the class of trimethyls. It is a potent inhibitor of tyrosine-specific protein kinases, including Bcr-Abl and Src family kinases. It has been shown to have antineoplastic properties in human cells in vitro. Imatinib is structurally similar to the anticancer agent lapatinib and inhibits G1 phase cell cycle progression by preventing phosphorylation of retinoblastoma protein (Rb). Imatinib is also genotoxic due to its structural similarity to other known genotoxic compounds such as bromo-2′-deoxyuridine and 2-chloroimidazole.

Propriedades químicas

• Peso molecular: 277.32 g/mol
• Fórmula: C₁₆H₁₅N₅
• Pureza: Min. 95%
• Cor/forma: Powder
• InChI: InChI=1S/C16H15N5/c1-11-4-5-13(17)9-15(11)21-16-19-8-6-14(20-16)12-3-2-7-18-10-12/h2-10H,17H2,1H3,(H,19,20,21)
• Chave InChI: InChIKey=QGAIPGVQJVGBIA-UHFFFAOYSA-N
• SMILES: Cc1ccc(N)cc1Nc1nccc(-c2cccnc2)n1