N-γ-Acetyl-N-2-formyl-5-methoxykynurenamine

CAS: 52450-38-1

Ref. 3D-FA17136

Informação sobre produto

• Nome: N-γ-Acetyl-N-2-formyl-5-methoxykynurenamine
• Sinónimos: N-[3-[2-(Formylamino)-5-methoxyphenyl]-3-oxopropyl]acetamideN1-Acetyl-N2-formyl-5-methoxykynuramineNSC 688263, AFMK, N-[3-[2-(Formylamino)-5-methoxyphenyl]-3-oxopropyl]acetamide, Acetamide, N-[3-[2-(formylamino)-5-methoxyphenyl]-3-oxopropyl]-, N1-Acetyl-N2-formyl-5-methoxykynuramine, NSC 688263

Descrição

N-gamma-Acetyl-N-2-formyl-5-methoxykynurenamine is a reactive metabolite that is produced by the enzyme tryptophan 2,3 dioxygenase (TDO). This compound has been shown to be a potent inducer of oxidative injury and neuronal death in vivo in humans. It targets enzymes involved in energy metabolism, such as mitochondrial membrane potential and polymerase chain reaction. N-gamma-Acetyl-N-2-formyl-5-methoxykynurenamine has been shown to cause oxidative stress in a model system. This reactive metabolite can also act as a fluorescence probe for melatonin or transfer reactions with other compounds to form fluorescent species.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 264.28 g/mol
• Fórmula: C₁₃H₁₆N₂O₄
• Pureza: Min. 95%
• Cor/forma: Beige Powder
• InChI: InChI=1S/C13H16N2O4/c1-9(17)14-6-5-13(18)11-7-10(19-2)3-4-12(11)15-8-16/h3-4,7-8H,5-6H2,1-2H3,(H,14,17)(H,15,16)
• Chave InChI: InChIKey=JYWNYMJKURVPFH-UHFFFAOYSA-N
• SMILES: COc1ccc(NC=O)c(C(=O)CCNC(C)=O)c1