N-Acetyl-S-(1,2-dichloroethenyl)-L-cysteine

CAS: 2148-31-4

Ref. 3D-FA17164

Informação sobre produto

• Nome: N-Acetyl-S-(1,2-dichloroethenyl)-L-cysteine
• Sinónimos: N-Acetyl-3-[(1,2-dichlorovinyl)thio]alanineS-(1,2-dichlorovinyl)-L-cysteine1,2-DCVMA, (R)-2-Acetamido-3-((1,2-dichlorovinyl)thio)propanoic acid, <span class="text-smallcaps">L</span>-Cysteine, N-acetyl-S-(1,2-dichloroethenyl)-, Alanine, N-acetyl-3-[(1,2-dichlorovinyl)thio]-, Alanine, N-acetyl-3-[(1,2-dichlorovinyl)thio]-, <span class="text-smallcaps">L</span>-, N-Acetyl S-(1,2-dichlorovinyl)-<span class="text-smallcaps">L</span>-cysteine, N-Acetyl-S-(1,2-dichloroethenyl)-<span class="text-smallcaps">L</span>-cysteine, N-Acetyl-S-(1,2-dichlorovinyl)-L-cysteine

Descrição

N-Acetyl-S-(1,2-dichloroethenyl)-L-cysteine is a reactive compound that is formed from the metabolism of acetaminophen. It has been shown to cause oxidative injury in the mitochondria of proximal tubule cells. N-Acetyl-S-(1,2-dichloroethenyl)-L-cysteine disrupts mitochondrial membrane potential and causes ATP depletion. It also causes mitochondrial dysfunction by inhibiting respiratory chain activity and lowering cytosolic calcium levels. N-Acetyl-S-(1,2-dichloroethenyl)-L-cysteine has been shown to be toxic in animals and humans. The main analytical method used to detect this compound is the tetrazolium dye assay.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 258.12 g/mol
• Fórmula: C₇H₉Cl₂NO₃S
• Pureza: Min. 95%
• InChI: InChI=1S/C7H9Cl2NO3S/c1-4(11)10-5(7(12)13)3-14-6(9)2-8/h2,5H,3H2,1H3,(H,10,11)(H,12,13)/b6-2+/t5-/m0/s1
• Chave InChI: InChIKey=LPPJGTSPIBSYQO-KDXUVAGDSA-N
• SMILES: CC(=O)N[C@@H](CS/C(Cl)=C/Cl)C(=O)O