Alcophosphamide
CAS: 52336-54-6
Ref. 3D-FA17268
1mg | A consultar | ||
2mg | A consultar | ||
5mg | A consultar | ||
10mg | A consultar | ||
25mg | A consultar |
Informação sobre produto
- N,N-Bis(2-chloroethyl)phosphorodiamidic acid 3-hydroxypropyl esterNSC 153182NSC 227248
- NSC 153182
- NSC 227248
- O-(3-Hydroxypropyl)-N,N-bis(2-chloroethyl)phosphorodiamidate
- Phosphorodiamidic acid, N,N-bis(2-chloroethyl)-, 3-hydroxypropyl ester
Alcophosphamide is an anticancer drug that inhibits the biological function of cells by interfering with DNA replication and protein synthesis. It binds to the DNA of cells, which prevents ribosomes from translating RNA into protein. Alcophosphamide is rapidly inactivated by deuterium isotope effect. The drug is excreted mainly through urine, but also partly through bile, where it may be hydrolyzed by liver enzymes to aldophosphamide. Alcophosphamide has been shown to inhibit matrix metalloproteinase (MMP) activity in human liver cells and cancer cell lines at high doses.
Propriedades químicas
Consulta técnica sobre: 3D-FA17268 Alcophosphamide
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