4-Aminosalicylic acid calcium salt heptahydrate

CAS: 133-15-3

Ref. 3D-FA172936

Informação sobre produto

• Nome: 4-Aminosalicylic acid calcium salt heptahydrate
• Sinónimos: 4-Amino-2-Hydroxy-Benzoic Acid, 4-Aminosalicylic acid calcium salt, Aminacyl, Aminosalicylate calcium, Benzoic acid, 4-amino-2-hydroxy-, calcium salt (2:1), Ca-PAS, Calcipas, Calcium 4-aminosalicylate, Calcium Bis(4-Amino-2-Hydroxybenzoate), Calcium aminosalicylate, Calcium p-aminosalicylate, Monocalcium p-aminosalicylate, P-Amino Salicylic Acid Calcium, Paracipan, Pasara calcium, Pasmicina, Salicylic acid, 4-amino-, calcium salt (2:1), p-Aminosalicylic acid calcium salt

Descrição

4-Aminosalicylic acid calcium salt heptahydrate is an anti-tuberculosis drug that belongs to the group of alkanoic acid derivatives. It is a major metabolite of 4-aminosalicylic acid, which is formed from the amino acid methionine by the enzyme phenol-O-methyltransferase. The compound inhibits bacterial growth and has been shown to be effective against strains of Mycobacterium tuberculosis resistant to traditional anti-tuberculosis drugs. 4-Aminosalicylic acid calcium salt heptahydrate also inhibits the production of inflammatory cytokines, such as tumor necrosis factor (TNF) in macrophages, and has been shown to have beneficial effects on bowel disease and inflammatory bowel disease. The mechanism of action may involve its ability to inhibit toll-like receptor 4 (TLR4), which leads to reduced expression of inflammatory genes.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 508.5 g/mol
• Fórmula: C₁₄H₁₀Ca₂N₂O₆·7H₂O
• Pureza: Min. 95%