6-Amino-2-methylthio-3-methyluracil

CAS: 54030-56-7

Ref. 3D-FA17467

Informação sobre produto

• Nome: 6-Amino-2-methylthio-3-methyluracil
• Sinónimos: 6-Amino-3-methyl-2-(methylthio)-4(3H)-pyrimidinone6-Amino-3-methyl-2-(methylsulfanyl)pyrimidin-4(3H)-oneNSC 57899, 6-Amino-3-methyl-2-(methylsulfanyl)-4(3H)-pyrimidinone, Pyrimidin-4(3H)-one, 6-amino-3-methyl-2-methylthio-

Descrição

6-Amino-2-methylthio-3-methyluracil is a pyrimidine nucleoside that inhibits the generation of cellular energy by inhibiting ribonucleotide reductase. It has been shown to be active against cancer cell lines in vitro and has no effect on normal cells. 6-Amino-2-methylthio-3-methyluracil is metabolized in vivo to uracil, which can form adducts with DNA bases and cause mutations. This drug also belongs to a class of β-unsaturated ketones that are known to have anticancer effects. 6-Amino-2-methylthio-3-methyluracil is used in cancer chemotherapy as an alternative treatment for cancer patients who have developed resistance to other drugs. The yield of this compound from the reaction is high, with yields of up to 90% reported.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 171.22 g/mol
• Fórmula: C₆H₉N₃OS
• Pureza: Min. 95%
• InChI: InChI=1S/C6H9N3OS/c1-9-5(10)3-4(7)8-6(9)11-2/h3H,7H2,1-2H3
• Chave InChI: InChIKey=LYWPZKCXMFJSGI-UHFFFAOYSA-N
• SMILES: CSc1nc(N)cc(=O)n1C