Informação sobre produto
- Isoquinoline-5-sulfonic acid N-(2-aminoethyl)amideN-(2-Aminoethyl)-5-isoquinolinesulfonic acid amide
- Aeiqs
- H-9
- H9
- Protein kinase C inhibitor H-9
- 5-Isoquinolinesulfonamide, N-(2-aminoethyl)-
- N-(2-aminoethyl)isoquinoline-5-sulfonamide
- 5-[(2-Ammonioethyl)Sulfamoyl]Isoquinolinium Dichloride
- 2-[(Isoquinolin-5-Ylsulfonyl)Amino]Ethanaminium
N-(2-Aminoethyl)-5-isoquinolinesulfonamide is a cyclic peptide that binds to the alpha subunit of guanine nucleotide regulatory protein (G protein). It is used as an immunosuppressant in the treatment of autoimmune diseases. N-(2-Aminoethyl)-5-isoquinolinesulfonamide inhibits the production of nitric oxide, which has been shown to contribute to the development of congestive heart failure and infectious diseases. This drug also has a depressant effect on neurons in the cerebellar granule layer.
N-(2-Aminoethyl)-5-isoquinolinesulfonamide binds to G protein by competitive inhibition, which prevents its interaction with other proteins and thus blocks signal transduction from G protein to adenylate cyclase. The binding site for this drug is located at the interface between alpha and beta subunits of G protein. This drug also inhibits
Propriedades químicas
Consulta técnica sobre: 3D-FA17737 N-(2-Aminoethyl)-5-isoquinolinesulfonamide
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