Ataciguat

CAS: 254877-67-3

Ref. 3D-FA18005

Informação sobre produto

• Nome: Ataciguat
• Sinónimos: 5-Chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfonyl)phenyl]benzamideHMR 1766
• Marca: Biosynth
• Descrição: Activator of soluble guanylyl cyclase (sGC) which stimulates cGMP production and is effective in cells under oxidative stress. Ataciguat stimulates the heme-free form of the sGC enzyme via the sGC N-terminus of β1-subunit. Ataciguat can promote vasorelaxation and hypotension by restoring or potentiating the nitric oxide (NO) signalling pathway.

Propriedades químicas

• Peso molecular: 576.5 g/mol
• Fórmula: C₂₁H₁₉Cl₂N₃O₆S₃
• Pureza: Min. 95%
• Cor/forma: Powder
• InChI: InChI=1S/C21H19Cl2N3O6S3/c22-14-1-6-18(25-34(28,29)20-8-7-19(23)33-20)17(13-14)21(27)24-15-2-4-16(5-3-15)35(30,31)26-9-11-32-12-10-26/h1-8,13,25H,9-12H2,(H,24,27)
• Chave InChI: InChIKey=PQHLRGARXNPFCF-UHFFFAOYSA-N
• SMILES: O=C(Nc1ccc(S(=O)(=O)N2CCOCC2)cc1)c1cc(Cl)ccc1NS(=O)(=O)c1ccc(Cl)s1