2-Amino-4-fluorophenol

CAS: 399-97-3

Ref. 3D-FA53922

Informação sobre produto

• Nome: 2-Amino-4-fluorophenol
• Sinónimos: 5-Fluoro-2-hydroxyaniline, 4-Fluoro-2-aminophenol, 5-Fluoro-2-hydroxy aniline, Aminofluorophenol1, Phenol, 2-amino-4-fluoro-

Descrição

2-Amino-4-fluorophenol is a synthetic chemical compound, which has been shown to have anti-inflammatory properties. It inhibits the production of inflammatory cytokines such as IL-1β, IL-6 and TNFα. 2-Amino-4-fluorophenol also inhibits the activity of cytochrome P450 enzymes responsible for the activation of prodrugs, including cyclophosphamide. This drug is currently being investigated as an anti-cancer agent because it appears to be selective for cancer cells and has been shown to inhibit cell proliferation in vitro. 2-Amino-4-fluorophenol binds to the heme moiety of cytochrome P450 by coordination with two nitrogen atoms and one oxygen atom found in the heme group, which helps stabilize this complex. The ligand field theory can be used to rationalize the binding affinity between 2-amino 4 fluoro phenol and the heme group by

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 127.12 g/mol
• Fórmula: C₆H₆FNO
• Pureza: Min. 95%
• Cor/forma: Powder
• InChI: InChI=1S/C6H6FNO/c7-4-1-2-6(9)5(8)3-4/h1-3,9H,8H2
• Chave InChI: InChIKey=ULDFRPKVIZMKJG-UHFFFAOYSA-N
• SMILES: Nc1cc(F)ccc1O