4-Amino-N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-ispobutylbenzenesulfonamide

CAS: 169280-56-2

Ref. 3D-FA58013

Informação sobre produto

• Nome: 4-Amino-N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-ispobutylbenzenesulfonamide
• Sinónimos: 4-Amino-(2R,3S)-N-(3-Amino-2-hydroxy-4-phenylbutyl)-N-isobutyl-benzenesulfonamide, 4-Amino-N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide, 4-Amino-N-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-(2-methylpropyl)benzenesulfonamide, 4-Amino-N-[(2r,3s)-3-Amino-2-Hydroxy-4-Phenyl butyl]-N-Isobutylbenzenesulfonamide(D7), Benzenesulfonamide, 4-amino-N-(3-amino-2-hydroxy-4-phenylbutyl)-N-(2-methylpropyl)-, [R-(R*,S*)]-, Benzenesulfonamide, 4-amino-N-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-(2-methylpropyl)-

Descrição

4-Amino-N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide is an amide that is used to treat HIV infections. It has been shown to have potent anti-viral activity against HIV infected cells in the laboratory and can inhibit the replication of HIV by interfering with the virus's ability to use the reverse transcriptase enzyme. 4ABAB has been shown to bind to the enzyme ribonuclease H (crth2), which is responsible for breaking down viral RNA. This binding prevents crth2 from cleaving viral RNA, thus inhibiting DNA synthesis and preventing cell death. 4ABAB also interferes with a hydrogen bond between ethyl group and the hydroxyl group on crth2, leading to a decrease in activity.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 391.53 g/mol
• Fórmula: C₂₀H₂₉N₃O₃S
• Pureza: Min. 95%
• Cor/forma: White Powder
• InChI: InChI=1S/C20H29N3O3S/c1-15(2)13-23(27(25,26)18-10-8-17(21)9-11-18)14-20(24)19(22)12-16-6-4-3-5-7-16/h3-11,15,19-20,24H,12-14,21-22H2,1-2H3/t19-,20+/m0/s1
• Chave InChI: InChIKey=NUMJNKDUHFCFJO-VQTJNVASSA-N
• SMILES: CC(C)CN(C[C@@H](O)[C@@H](N)Cc1ccccc1)S(=O)(=O)c1ccc(N)cc1