Atorvastatin calcium salt trihydrate

CAS: 344423-98-9

Ref. 3D-FA60421

Informação sobre produto

• Nome: Atorvastatin calcium salt trihydrate
• Sinónimos: 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, calcium salt (2:1), trihydrate, (βR,δR)-, 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, calcium salt, hydrate (2:1:3), (βR,δR)-, Atorvastatin Calcium Trihydrate, Atorvastatin calcium sesquihydrate, Atorvastatin hemicalcium sesquihydrate, Atorvastatin hemicalcium trihydrate, Lipitor

Descrição

Atorvastatin is a cholesterol-lowering drug that belongs to the class of statins. It is used for the treatment of dyslipidemias, cardiovascular disease, and other conditions. Atorvastatin is a prodrug that is metabolized by the liver into atorvastatin calcium, its active form. The metabolism of atorvastatin occurs through side-chain cleavage by cytochrome P450 enzymes and hydroxylation by cytochrome P450 enzymes. This drug has been shown to inhibit atherosclerotic lesion formation in mice with diet-induced hypercholesterolemia. Atorvastatin also inhibits miapaca-2 cells without affecting human serum lipid profiles, which may be due to its low potency.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 1,209.39 g/mol
• Fórmula: C₆₆H₆₈CaF₂N₄O₁₀·3H₂O
• Pureza: Min. 98 Area-%
• Cor/forma: White Off-White Powder