Retigabine

CAS: 150812-12-7

Ref. 3D-FA61501

Informação sobre produto

• Nome: Retigabine
• Sinónimos: 2-Amino-4-(4-fluorbenzylamino)-1-ethoxycarbonylaminobenzene, 2-Amino-4-(4-Fluorbenzylamino)-1-Ethoxycarbonylaminobenzene, Carbamic acid, N-[2-amino-4-[[(4-fluorophenyl)methyl]amino]phenyl]-, ethyl ester, Carbamic acid, [2-amino-4-[[(4-fluorophenyl)methyl]amino]phenyl]-, ethyl ester, D 23129, D2312, Ethyl [2-amino-4-[[(4-fluorophenyl)methyl]amino]phenyl]carbamate, Ethyl {2-Amino-4-[(4-Fluorobenzyl)Amino]Phenyl}Carbamate, Ezogabine, Gke 841, Gw 582892X, N-(2-Amino-4-(4-fluorobenzylamino)phenyl)carbamic Acid Ethyl Ester, Potiga, Retigabin, RetigabineDiscontinued See: R189051, Trobalt, Way 143841, [2-Amino-4-(4-fluoro-benzylamino)-phenyl]-carbamic acid ethyl ester
• CAS: 150812-12-7

Descrição

Retigabine is a carbamate that binds to the benzodiazepine binding site of the gamma-aminobutyric acid receptor. It has been shown to have analgesic properties in animal studies, and has also been investigated as a potential treatment for epilepsy. Retigabine may be used in combination with other drugs, such as flumazenil, which can reverse its effects. The structural analog of retigabine is flumazenil, a drug that can reverse the effects of benzodiazepines such as diazepam and midazolam. Retigabine also interacts with other drugs through significant effects on their pharmacokinetics and pharmacodynamics.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 303.33 g/mol
• Fórmula: C₁₆H₁₈FN₃O₂
• Pureza: Min. 98 Area-%
• Cor/forma: White Powder
• InChI: InChI=1S/C16H18FN3O2/c1-2-22-16(21)20-15-8-7-13(9-14(15)18)19-10-11-3-5-12(17)6-4-11/h3-9,19H,2,10,18H2,1H3,(H,20,21)
• Chave InChI: InChIKey=PCOBBVZJEWWZFR-UHFFFAOYSA-N
• SMILES: CCOC(=O)Nc1ccc(NCc2ccc(F)cc2)cc1N