AZD 4547

CAS: 1035270-39-3

Ref. 3D-FA64951

Informação sobre produto

• Nome: AZD 4547
• Sinónimos: N-(5-(3,5-dimethoxyphenethyl)-1H-pyrazol-3-yl)-4-((3S,5R)-3,5-dimethylpiperazin-1-yl)benzamide, Azd4547
• CAS: 1035270-39-3

Descrição

Inhibitor of fibroblast growth factor receptors (FGFR1, FGFR2 and FGFR3). Demonstrated anti-tumor effects in pre-clinical models of FGFR-driven tumors. AZD 4547 resulted in tumor progression when applied on a patient-derived model of FGFR1-amplified squamous cell lung disease. Antineoplastic effects also observed in FGFR2-amplified gastric cancer.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 463.57 g/mol
• Fórmula: C₂₆H₃₃N₅O₃
• Pureza: Min. 95%
• Cor/forma: Powder
• InChI: InChI=1S/C26H33N5O3/c1-17-15-31(16-18(2)27-17)22-9-6-20(7-10-22)26(32)28-25-13-21(29-30-25)8-5-19-11-23(33-3)14-24(12-19)34-4/h6-7,9-14,17-18,27H,5,8,15-16H2,1-4H3,(H2,28,29,30,32)/t17-,18+
• Chave InChI: InChIKey=VRQMAABPASPXMW-HDICACEKSA-N
• SMILES: COc1cc(CCc2cc(NC(=O)c3ccc(N4C[C@H](C)N[C@H](C)C4)cc3)n[nH]2)cc(OC)c1