5-Amino-2-fluorobenzoic acid

CAS: 56741-33-4

Ref. 3D-FA70089

Informação sobre produto

• Nome: 5-Amino-2-fluorobenzoic acid
• Sinónimos: 3-(Difluoromethoxy)-1,1,1,2,2-pentafluoropropane, Difluoromethyl 2,2,3,3,3-pentafluoropropyl ether, Propane, 3-(Difluoromethoxy)-1,1,1,2,2-Pentafluoro-, 5-Amino-2-fluoro-benzoic acid, 5-Amino-2-fluorobenziocacid, 5-Amino-2-Fluorobenzioc Acid

Descrição

5-Amino-2-fluorobenzoic acid (5AFBA) is a synthetic aniline that is used as a fluoroquinolone antibiotic. 5AFBA inhibits the synthesis of trehalose, which is vital for bacterial growth. This drug also has been shown to be active against Mycobacterium tuberculosis and Mycobacterium avium complex. 5AFBA has also been shown to have antifungal properties, inhibiting the synthesis of ergosterol in the fungal cell membrane. 5AFBA can be modified by alkylation with geranyl groups or N-methylation at the amino group. These modifications have been shown to increase its antibacterial activity against Pseudomonas aeruginosa.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 155.13 g/mol
• Fórmula: C₇H₆FNO₂
• Cor/forma: Powder
• InChI: InChI=1S/C7H6FNO2/c8-6-2-1-4(9)3-5(6)7(10)11/h1-3H,9H2,(H,10,11)
• Chave InChI: InChIKey=WYGAIOJWQDRBRJ-UHFFFAOYSA-N
• SMILES: Nc1ccc(F)c(C(=O)O)c1