7-[3-[4-[Bis(4-Fluorophenyl)-Hydroxymethyl]Piperidin-1-Yl]Propoxy]-6-Methoxychromen-2-One

CAS: 145574-90-9

Ref. 3D-FB101646

Informação sobre produto

• Nome: 7-[3-[4-[Bis(4-Fluorophenyl)-Hydroxymethyl]Piperidin-1-Yl]Propoxy]-6-Methoxychromen-2-One
• Sinónimos: Scopinast [INN], 7-(3-(4-(Bis(p-fluorophenyl)hydroxymethyl)piperidino)propoxy)-6-methoxycoumarin, Unii-Lz9041E1Bo, 7-(3-{4-[bis(4-fluorophenyl)(hydroxy)methyl]piperidin-1-yl}propoxy)-6-methoxy-2H-chromen-2-one

Descrição

7-[3-[4-[Bis(4-Fluorophenyl)-Hydroxymethyl]Piperidin-1-Yl]Propoxy]-6-Methoxychromen-2-One is a prodrug that is converted to the active form 6-Methoxychromen-2,7-(3H)one (EMC) in vivo. The drug binds to DNA and RNA by forming a covalent bond with the N7 position of guanine. It has been shown to have activity against methicillin resistant Staphylococcus aureus and Mycobacterium avium complex. The drug is insoluble in water, but can be dissolved in solvents such as dimethylsulfoxide or acetonitrile. 7-[3-[4-[Bis(4-Fluorophenyl)-Hydroxymethyl]Piperidin-1-Yl]Propoxy]-6-

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 535.58 g/mol
• Fórmula: C₃₁H₃₁F₂NO₅
• Pureza: Min. 95%
• InChI: InChI=1S/C31H31F2NO5/c1-37-28-19-21-3-12-30(35)39-27(21)20-29(28)38-18-2-15-34-16-13-24(14-17-34)31(36,22-4-8-25(32)9-5-22)23-6-10-26(33)11-7-23/h3-12,19-20,24,36H,2,13-18H2,1H3
• Chave InChI: InChIKey=JRXHLMMVJSXXHZ-UHFFFAOYSA-N
• SMILES: COc1cc2ccc(=O)oc2cc1OCCCN1CCC(C(O)(c2ccc(F)cc2)c2ccc(F)cc2)CC1