Diacylglycerol kinase inhibitor II

CAS: 120166-69-0

Ref. 3D-FB102452

Informação sobre produto

• Nome: Diacylglycerol kinase inhibitor II
• Sinónimos: 3-[2-[4-[Bis(4-fluorophenyl)methylene]-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone
• CAS: 120166-69-0

Descrição

Diacylglycerol kinase inhibitor II is a transcriptional regulator that inhibits diacylglycerol kinase. This inhibitor blocks the signaling pathways for growth factor-β1 by inhibiting the enzyme phosphatidic acid phosphatase, which plays an important role in cellular proliferation and migration. Diacylglycerol Kinase Inhibitor II has also been shown to inhibit cation channels and calcium release from intracellular stores. Diacylglycerol Kinase Inhibitor II binds to both cytosolic and nuclear proteins. It has been shown to inhibit cell proliferation and induce apoptosis in breast cancer cells.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 489.58 g/mol
• Fórmula: C₂₈H₂₅F₂N₃OS
• Pureza: Min. 97 Area-%
• Cor/forma: Powder
• InChI: InChI=1S/C28H25F2N3OS/c29-22-9-5-19(6-10-22)26(20-7-11-23(30)12-8-20)21-13-15-32(16-14-21)17-18-33-27(34)24-3-1-2-4-25(24)31-28(33)35/h1-12H,13-18H2,(H,31,35)
• Chave InChI: InChIKey=ZCNBZFRECRPCKU-UHFFFAOYSA-N
• SMILES: O=c1c2ccccc2[nH]c(=S)n1CCN1CCC(=C(c2ccc(F)cc2)c2ccc(F)cc2)CC1