5-Bromo-2-chloro-3-nitropyridine

CAS: 67443-38-3

Ref. 3D-FB10581

Informação sobre produto

• Nome: 5-Bromo-2-chloro-3-nitropyridine
• Sinónimos: 2-Pyridinecarboxylic Acid, 5-Bromo-, 5-Bromo-2-Carboxypyridine, 5-Bromo-2-Picolinic Acid, Iflab-Bb F1957-0001, Rarechem Al Bo 2390
• CAS: 67443-38-3

Descrição

5-Bromo-2-chloro-3-nitropyridine is a chemical compound that has been shown to have anticancer activity. It has been found to inhibit the phosphoinositide 3 kinase (PI3K) and the mammalian target of rapamycin complex 1 (mTORC1). This drug is also a potent inhibitor of the kinase shp2, which regulates cell proliferation and apoptosis. 5-Bromo-2-chloro-3-nitropyridine inhibits tumor growth in vitro and in vivo. The mechanism of this inhibition may be due to 5-bromo-2,3 nitropyridine's ability to inhibit inflammatory genes such as NFκβ, IL1β, and IL6. 5 - Bromo - 2 - chloro - 3 - nitropyridine has also been shown to inhibit death pathways in cells by inhibiting proapoptotic protein Bax.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 237.44 g/mol
• Fórmula: C₅H₂BrClN₂O₂
• Pureza: Min. 95%
• Cor/forma: Powder