3-bromo-4-(trifluoromethyl)aniline
CAS: 172215-91-7
Ref. 3D-FB105848
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Informação sobre produto
3-bromo-4-(trifluoromethyl)aniline is an intermediate in the synthesis of various pharmaceuticals. It can be prepared by regioselective synthesis from methoxybenzene and trifluoroacetic acid. The yield for this reaction is about 50%. This compound reacts preferentially at the bifunctional carbon, which has a functional group with a high electron density. 3-bromo-4-(trifluoromethyl)aniline can be made by reacting butyllithium with 3-bromobenzaldehyde and then adding fluorine gas to the resulting intermediate. The reactivity of this compound depends on the position of fluorine. If it is on a terminal carbon, it will react more easily than if it is on an internal carbon.
Propriedades químicas
Consulta técnica sobre: 3D-FB105848 3-bromo-4-(trifluoromethyl)aniline
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