2-Bromo-N-(2-methoxyphenyl)acetamide

CAS: 32428-69-6

Ref. 3D-FB120400

Informação sobre produto

• Nome: 2-Bromo-N-(2-methoxyphenyl)acetamide
• Sinónimos: acetamide, 2-bromo-N-(2-methoxyphenyl)-, acetamide, 2-bromo-N-(2-methoxyphenyl)-

Descrição

2-Bromo-N-(2-methoxyphenyl)acetamide is a drug that belongs to the class of antituberculosis drugs. It inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. 2-Bromo-N-(2-methoxyphenyl)acetamide also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture. 2-Bromo-N-(2-meth

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 244.09 g/mol
• Fórmula: C₉H₁₀BrNO₂
• Pureza: Min. 95%
• InChI: InChI=1S/C9H10BrNO2/c1-13-8-5-3-2-4-7(8)11-9(12)6-10/h2-5H,6H2,1H3,(H,11,12)
• Chave InChI: InChIKey=DMOPLFALZWOOTI-UHFFFAOYSA-N
• SMILES: COc1ccccc1NC(=O)CBr