3-tert-Butyl-isoxazol-5-ylamine

CAS: 59669-59-9

Ref. 3D-FB13151

Informação sobre produto

• Nome: 3-tert-Butyl-isoxazol-5-ylamine
• Sinónimos: 3-Isoxazolamine, 5-(1,1-dimethylethyl)-, 5-tert-Butyl-1,2-oxazol-3-amine, 3-Tert-Butyl-1,2-Oxazol-5-Amine, 5-Isoxazolamine, 3-(1,1-dimethylethyl)-, 5-Tert-Butylisoxazol-3-Amine, 3-Tert-Butylisoxazol-5-Amine

Descrição

3-tert-Butyl-isoxazol-5-ylamine (3TBI) is a tyrosine kinase inhibitor that has been shown to be effective in inhibiting the proliferation of human prostate cancer cells, as well as the growth of tumours. 3TBI has also been shown to inhibit neuronal apoptosis and relieve neuropathic pain. Computational modelling has shown that 3TBI binds to the ATP binding site on the enzyme and blocks ATP hydrolysis, which prevents phosphorylation of tyrosine residues. This inhibition leads to a decrease in protein synthesis and cell death.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 140.18 g/mol
• Fórmula: C₇H₁₂N₂O
• Pureza: Min. 95%
• Cor/forma: Powder
• InChI: InChI=1S/C7H12N2O/c1-7(2,3)5-4-6(8)10-9-5/h4H,8H2,1-3H3
• Chave InChI: InChIKey=APHNQOGPYLTSFX-UHFFFAOYSA-N
• SMILES: CC(C)(C)c1cc(N)on1