Informação sobre produto
Nome:
(R,R)-KW3049
Descrição:
(R,R)-KW3049 is a selective inhibitor of the enzyme cGMP-specific 3',5'-cyclic phosphodiesterase (PDE3B) and has been shown to inhibit the proliferation of human epidermal keratinocytes. It has also been shown to reduce the ventricular mass index in chronic kidney disease patients with heart failure. The long-term efficacy of this drug has been demonstrated in clinical studies. This drug's mechanism of action is not fully understood, but it appears to work by regulating the levels of intracellular Ca2+ ions. This inhibition may be due to its ability to sequester extracellular Ca2+ ions into cells or by inhibiting the production of cGMP, which is required for the activation of protein kinase G (PKG).
Aviso:
Os nossos productos estão destinados exclusivamente para uso em laboratório. Para qualquer outra aplicação, por favor entre em contacto.
Marca:
Biosynth
Armazenamento a longo prazo:
Notas:
Propriedades químicas
Peso molecular:
542.02 g/mol
Fórmula:
C28H32ClN3O6
Pureza:
Min. 95%
MDL:
Ponto de fusão:
Ponto de ebulição:
Ponto de inflamação:
Densidade:
Concentração:
EINECS:
Merck:
Código HS:
