tert-Butyl sulfamoylcarbamate
CAS: 148017-28-1
Ref. 3D-FB142916
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| 2g | A consultar | |
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| 500mg | A consultar |
Informação sobre produto
- 1,1-Dimethylethyl N-(aminosulfonyl)carbamate
- BOC-Sulfamide
- Carbamic acid, (aminosulfonyl)-, 1,1-dimethylethyl ester
- Carbamic acid, N-(aminosulfonyl)-, 1,1-dimethylethyl ester
- N-(Aminosulfonyl)carbamic acid 1,1-dimethylethyl ester
- Tert-Butyl Sulfamoylcarbamate
- tert-Butoxycarbonylsulfamide
- tert-Butyl N-(sulfamoyl)carbamate
Tert-Butyl sulfamoylcarbamate is an antibacterial agent which inhibits the growth of gram-negative bacteria by binding to the active site of β-lactamase enzymes. It has been shown to be effective against Pseudomonas aeruginosa, a common cause of hospital infections. This compound is also used as a protective agent in amines and sulfuric acid esters, such as sulfonyl chlorides. Tert-butyl sulfamoylcarbamate can be synthesized by reacting tert-butyl carbamate with chloroacetic acid in an exothermic reaction at cryogenic temperatures. The reaction can be conducted under basic conditions or in the presence of a base catalyst, such as potassium hydroxide or sodium ethoxide. Tert-Butyl sulfamoylcarbamate can be isolated by removing solvent in vacuo and recrystallizing from diethylether at reaction temperatures below 30°C.
Propriedades químicas
Consulta técnica sobre: 3D-FB142916 tert-Butyl sulfamoylcarbamate
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