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7-Bromothieno[2,3-b]pyrazine
CAS: 1126824-72-3
Ref. 3D-FB156284
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Informação sobre produto
7-Bromothieno[2,3-b]pyrazine is a synthetic compound that has been shown to inhibit the kinase activity of IL-1 receptor in vitro. IL-1 receptor is a member of the class of protein tyrosine kinases. The binding of 7-bromothieno[2,3-b]pyrazine to IL-1 receptor inhibits the signalling of interleukin 1 (IL-1) and other cytokines that are involved in inflammatory diseases. This inhibition may be due to its selectivity for IL-1 receptor and its potency at low concentrations. 7-Bromothieno[2,3-b]pyrazine binds to the ATP site on IL-1 receptor and alters the shape of this protein by introducing a pyrazolopyrimidine moiety into its ATP site.
Propriedades químicas
Consulta técnica sobre: 3D-FB156284 7-Bromothieno[2,3-b]pyrazine
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