4-Benzyloxygramine
CAS: 13523-95-0
Ref. 3D-FB18512
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Informação sobre produto
- N,N-Dimethyl-4-(phenylmethoxy)-1H-indole-3-methanamine
4-Benzyloxygramine is an alkaloid that is a benzyl derivative of the indole nucleus. It has been shown to be an antagonist of lithium, calcium and potassium channels. The synthesis of 4-benzyloxyindole from 2-methyl-3-nitrophenol was achieved through a convergent approach. The debenzylated product was hydrolyzed with sodium hydroxide in water, followed by decarboxylation with aluminium chloride to form the desired product. 4-Benzyloxygramine reacts with benzaldehyde in the presence of potassium hydroxide to form 4-benzyloxyindole. This reaction involves an elimination of hydrogen bromide and formation of a double bond between carbon atoms 3 and 4 on the indole ring.
Propriedades químicas
Consulta técnica sobre: 3D-FB18512 4-Benzyloxygramine
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