7-Bromoquinoline

CAS: 4965-36-0

Ref. 3D-FB33282

Informação sobre produto

• Nome: 7-Bromoquinoline
• Sinónimos: Quinoline, 7-Bromo-
• CAS: 4965-36-0

Descrição

7-Bromoquinoline is a synthetic molecule that was first synthesized in the early 1980s. It is an analog of 7-bromoquinoline, which has been shown to have cytotoxic properties against cancer cells. The synthesis of 7-bromoquinoline involves a cross-coupling reaction with chloroacetonitrile and N-methylformamide. The nmr spectra for this compound are very similar to those for 7-bromoquinoine, but it lacks the secondary amine peak at δ 10.7 ppm. Primary culture cells were used to test the bioactivity of 7-bromoquinoline, and these cells were disrupted by adding trypsin after incubation with various concentrations of 7-bromoquinoline. This study showed that the quinoline derivatives had cytotoxic effects on cultured cells at low concentrations, suggesting that they may be useful as anticancer agents. Molecular modeling studies show that

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 208.05 g/mol
• Fórmula: C₉H₆BrN
• Pureza: Min. 95%
• Cor/forma: Powder
• InChI: InChI=1S/C9H6BrN/c10-8-4-3-7-2-1-5-11-9(7)6-8/h1-6H
• Chave InChI: InChIKey=XYBSZCUHOLWQQU-UHFFFAOYSA-N
• SMILES: Brc1ccc2cccnc2c1