2-Bromo-4-chlorobenzoic acid

CAS: 936-08-3

Ref. 3D-FB38481

Informação sobre produto

• Nome: 2-Bromo-4-chlorobenzoic acid

Descrição

2-Bromo-4-chlorobenzoic acid (2BCBA) is a potent inhibitor of the hepatitis C virus NS5B polymerase. It has been shown to inhibit the growth of cancer cells in vitro. 2BCBA binds to the active site of the NS5B polymerase, which is essential for viral replication. In addition, it has been found to have synergistic effects with other anti-hepatitis drugs such as interferon. The binding affinity of 2BCBA and its derivatives to NS5B polymerase are determined by their interaction energies and also by their ability to form supramolecular complexes with this enzyme. The inhibition constants for 2BCBA were calculated using high performance liquid chromatography (HPLC). This drug is an isomeric compound that can exist in two different forms: cis and trans.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 235.46 g/mol
• Fórmula: C₇H₄BrClO₂
• Pureza: Min. 95%
• Cor/forma: Powder
• InChI: InChI=1S/C7H4BrClO2/c8-6-3-4(9)1-2-5(6)7(10)11/h1-3H,(H,10,11)
• Chave InChI: InChIKey=USMQLFCVCDEXAK-UHFFFAOYSA-N
• SMILES: O=C(O)c1ccc(Cl)cc1Br