5-Bromo-1H-indazole
CAS: 53857-57-1
Ref. 3D-FB50830
| 1g | A consultar | ||
| 2g | A consultar | ||
| 5g | A consultar | ||
| 10g | A consultar | ||
| 25g | A consultar |
Informação sobre produto
- 5-Bromoindazole
- 5-Bromoindazol
5-Bromo-1H-indazole is an indazole derivative that has been shown to have potential use in the treatment of pain. It binds to the allosteric site on the enzyme gyrase, which is a DNA topoisomerase that controls the supercoiling of DNA. This binding prevents ATP from binding and inhibits DNA unwinding, leading to a decrease in DNA synthesis and cell division. 5-Bromo-1H-indazole also binds with high affinity at the allosteric site on the enzyme adenylate cyclase, which is involved in signal transduction pathways. Binding of 5-bromo-1H-indazole causes an increase in cAMP levels and leads to functional effects such as antinociception.
Propriedades químicas
Consulta técnica sobre: 3D-FB50830 5-Bromo-1H-indazole
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