3-(4-Bromobenzoyl)propionic acid

CAS: 6340-79-0

Ref. 3D-FB53808

Informação sobre produto

• Nome: 3-(4-Bromobenzoyl)propionic acid
• Sinónimos: 4-(4-Bromophenyl)-4-oxobutanoic acid, 3-(4-Bromobenzoyl)propanoic acid, 3-(p-Bromobenzoyl)propionic acid, 4-(4-Bromophenyl)-4-Oxobutanoate, 4-(4-Bromophenyl)-4-Oxobutanoic Acid, 4-(4-Bromophenyl)-4-oxobutyric acid, 4-Bromo-γ-oxobenzenebutanoic acid, Benzenebutanoic acid, 4-bromo-γ-oxo-, Nsc 51068, Propionic acid, 3-(p-bromobenzoyl)-, p-Bromobenzoylpropionic acid, β-(4-Bromobenzoyl)propionic acid, β-(4-Bromophenyl)propionic acid

Descrição

3-(4-Bromobenzoyl)propionic acid (4-BBPA) is an naphthalene derivative that has been shown to have antibacterial activity. 4-BBPA binds to the bacterial 16S ribosomal RNA, inhibiting protein synthesis and leading to cell death. It has been synthesised and expressed in bacteria, as well as being synthesised from a chemical precursor. 4-BBPA can cause apoptosis in human glioblastoma cells by inducing annexin II and releasing cytochrome c from mitochondria. This drug also has chemoresistance properties which may be due to its ability to inhibit the expression of the gene for drug efflux pump PgP.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 257.08 g/mol
• Fórmula: C₁₀H₉BrO₃
• Pureza: Min. 95%
• InChI: InChI=1S/C10H9BrO3/c11-8-3-1-7(2-4-8)9(12)5-6-10(13)14/h1-4H,5-6H2,(H,13,14)
• Chave InChI: InChIKey=ZODFRCZNTXLDDW-UHFFFAOYSA-N
• SMILES: O=C(O)CCC(=O)c1ccc(Br)cc1