4-Cyanoindole

CAS: 16136-52-0

Ref. 3D-FC03444

Informação sobre produto

• Nome: 4-Cyanoindole
• Sinónimos: 4-Indolecarbonitrile, 1H-indole-4-carbonitrile

Descrição

The 4-cyanoindole is a fluorescent molecule that binds to proteins and affects protein homeostasis. It has been shown to bind to the sodium salt form of proteins, which are typically found in human liver cells. The binding of 4-cyanoindole to these proteins leads to its reduction by borohydride and fluorescence resonance energy transfer (FRET) between the molecule and the protein. This binding can be detected using a fluorescence lifetime spectroscopy technique, which detects changes in the fluorescence's lifetime as well as intensity. The binding of 4-cyanoindole to proteins has been shown to have anti-cancer properties. It has also been used for detection of monoclonal antibodies against cancer cells or for fluorescent labeling of cancer cells for immunofluorescent microscopy.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 142.16 g/mol
• Fórmula: C₉H₆N₂
• Cor/forma: White Powder
• InChI: InChI=1S/H3N/h1H3
• Chave InChI: InChIKey=QGZKDVFQNNGYKY-UHFFFAOYSA-N
• SMILES: N#Cc1cccc2[nH]ccc12