6-[[4-(3-Chloro-2-fluorobenzoyl)piperazin-1-yl]methyl]-N-(thiazol-2-yl)pyridin-2-amine

CAS: 885325-71-3

Ref. 3D-FC101345

Informação sobre produto

• Nome: 6-[[4-(3-Chloro-2-fluorobenzoyl)piperazin-1-yl]methyl]-N-(thiazol-2-yl)pyridin-2-amine

Descrição

Nilotinib is a drug used in the treatment of cancer. It is a potent inhibitor of tyrosine kinase, which blocks the signalling pathway that leads to cell growth and division. Nilotinib has been shown to be effective against cancers that have a mutation in the Abl gene, such as chronic myeloid leukaemia. The drug also inhibits receptor protein tyrosine kinase Bcr-Abl, which is found in chronic myeloid leukaemia cells from patients who are resistant to imatinib therapy. Nilotinib binds to specific sirna (small interfering ribonucleic acid) sequences on the mRNA molecule and prevents it from being translated into protein. This binding regulates the production of proteins involved in tumour growth and proliferation by inhibiting the activity of certain genes known as proto-oncogenes. It also enhances the effectiveness of other drugs used for cancer treatment by modulating or enhancing their effects on tumours.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 431.92 g/mol
• Fórmula: C₂₀H₁₉ClFN₅OS
• Pureza: Min. 95%