1-Cyclopropyl-8-(Difluoromethoxy)-6-Fluoro-7-[(3S)-3-Methylpiperazin-1-Yl]-4-Oxoquinoline-3-Carboxylic Acid

CAS: 153808-85-6

Ref. 3D-FC102855

Informação sobre produto

• Nome: 1-Cyclopropyl-8-(Difluoromethoxy)-6-Fluoro-7-[(3S)-3-Methylpiperazin-1-Yl]-4-Oxoquinoline-3-Carboxylic Acid
• Sinónimos: Caderofloxacin, 1-cyclopropyl-8-(difluoromethoxy)-6-fluoro-7-[(3S)-3-methylpiperazin-1-yl]-4-oxo-quinoline-3-carboxylic acid, 1-cyclopropyl-8-(difluoromethoxy)-6-fluoro-7-[(3S)-3-methylpiperazin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Descrição

Gatifloxacin is a fluoroquinolone antibiotic that inhibits the DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. It binds to bacterial 16S ribosomal RNA and inhibits protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division. Gatifloxacin has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. Gatifloxacin has shown anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 411.38 g/mol
• Fórmula: C₁₉H₂₀F₃N₃O₄
• Pureza: Min. 95%
• InChI: InChI=1S/C19H20F3N3O4/c1-9-7-24(5-4-23-9)15-13(20)6-11-14(17(15)29-19(21)22)25(10-2-3-10)8-12(16(11)26)18(27)28/h6,8-10,19,23H,2-5,7H2,1H3,(H,27,28)/t9-/m0/s1
• Chave InChI: InChIKey=QBDBUKJBJJWZMG-VIFPVBQESA-N
• SMILES: C[C@H]1CN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2OC(F)F)CCN1