1-Chloro-2-iodo-4-(trifluoromethyl)benzene
CAS: 672-57-1
Ref. 3D-FC106203
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Informação sobre produto
- 1-Chloro-2-iodo-4-trifluoromethylbenzene
- 2-Chloro-1-iodo-5-trifluoromethylbenzene
- 4-Chloro-3-Iodobenzotrifluoride
- Benzene, 1-chloro-2-iodo-4-(trifluoromethyl)-
- NSC 89703
- Toluene, 4-chloro-α,α,α-trifluoro-3-iodo-
1-Chloro-2-iodo-4-(trifluoromethyl)benzene is a triphenylene compound that has been shown to be an inhibitor of cytochrome P450. It binds to the heme moiety of the enzyme, which prevents oxygen from binding and inhibits mitochondrial respiration. 1-Chloro-2-iodo-4-(trifluoromethyl)benzene is known to cause hepatotoxicity in rats, with a dose dependent response. The trifluoromethyl group enhances this effect, as it increases the solubility of the compound in fat. The biphenylene moiety increases its toxicity by increasing the metabolic rate and inhibiting protein synthesis. Halogens such as chlorine or bromine increase the reactivity of 1-chloro-2-iodo-4-(trifluoromethyl)benzene by adding electron density to the molecule and
Propriedades químicas
Consulta técnica sobre: 3D-FC106203 1-Chloro-2-iodo-4-(trifluoromethyl)benzene
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