6-Chloropyridazine-3-thiol

CAS: 3916-78-7

Ref. 3D-FC121917

Informação sobre produto

• Nome: 6-Chloropyridazine-3-thiol
• Sinónimos: 6-Chloro-3-pyridazinethiol, 3(2H)-Pyridazinethione, 6-chloro-, 3-Pyridazinethiol, 6-Chloro-, 6-Chloro-3(2H)-pyridazinethione, T6Nmyj Cus Fg, T6Nnj Csh Fg

Descrição

6-Chloropyridazine-3-thiol is a potent inhibitor of platelet aggregation. This drug binds to the active site of the enzyme ADP-thrombin, thereby blocking the conversion of ADP to thrombin. 6-Chloropyridazine-3-thiol has been shown to have a high affinity for human liver microsomes, and is metabolized by conjugation with glutathione or glucuronide. 6CpT also inhibits the activation of factor V and factor VIII, which are involved in blood clotting. It is hypothesized that this inhibition may be due to its ability to bind to reactive chlorine atoms found on these proteins. 6-Chloropyridazine-3-thiol is a potent inhibitor of platelet aggregation, but it does not show any antiplatelet activity when used at low doses.

• Marca: Biosynth

Propriedades químicas

• Peso molecular: 146.6 g/mol
• Fórmula: C₄H₃ClN₂S
• Pureza: Min. 95%
• Cor/forma: White Powder
• InChI: InChI=1S/C4H3ClN2S/c5-3-1-2-4(8)7-6-3/h1-2H,(H,7,8)
• Chave InChI: InChIKey=ABQHEWLZYZQXHY-UHFFFAOYSA-N
• SMILES: S=c1ccc(Cl)n[nH]1